Ancient Kostenki 14 (Markina Gora) DNA: A Glimpse into a Population on Its Way from America to Africa
Science DOI: 10.1126/science.aaa0114 Genomic Structure in Europeans Dating Back at Least 36,200 Years Andaine Seguin-Orlando, Thorfinn S. Korneliussen, Martin Sikora, Anna-Sapfo Malaspinas, Andrea Manica, Ida Moltke, Anders Albrechtsen, Amy Ko, Ashot Margaryan, Vyacheslav Moiseyev, Ted Goebel, Michael Westaway, David Lambert,…
Ancient Ust’-Ishim DNA as Seen From the Americas
Nature 514, 445–449 (23 October 2014) doi:10.1038/nature13810 Genome sequence of a 45,000-year-old modern human from western Siberia Qiaomei Fu, Heng Li, Priya Moorjani, Flora Jay, Sergey M. Slepchenko, Aleksei A. Bondarev, Philip L. F. Johnson, Ayinuer Aximu-Petri, Kay Prufer, Cesare de Filippo,…
Ancient DNA from Mal’ta and Afontova Gora: A Full Account
Courtesy Alexander Kim, the long-awaited paper by the Eske Willerslev team became finally available to me. This is obviously not the last word on the subject of Amerindian origins, and the David Reich Lab has a different interpretation of ancient…
A Closer Look at Human and Neandertal Mitogenomes
In one of my comments on Anthrogenica.com, I mistakenly denied that Behar et al. (2012) reported the two mutations A2758G and G7146A shared between late European Neandertals and the modern human L2’3’4’5’6 clade. As a reminder, A2758G and G7146A were highlighted in…
The End of Out-of-Africa: A Copernican Reassessment of the Patterns of Genetic Variation in the Old World
Over at Anthrogenica, I’ve been having some heated (as always) but this time also productive discussions regarding the interpretation of currently available genetic evidence. In the following I will sketch out a hypothesis that increasingly makes sense to me. 1….
A Signal of Neandertal Admixture in Modern Human mtDNA?
Russian Journal of Genetics, September 2013, Vol. 49, No. 9, 975-978 Mitochondrial DNA Polymorphisms Shared Between Modern Humans and Neanderthals: Adaptive Convergence or Evidence for Interspecific Hybridization Malyarchuk, Boris A. Abstract An analysis of the variability of the nucleotide sequences in the…
The Last Common Ancestor of Modern Humans and Neandertals Still a Mystery
Proceedings of the National Academy of Sciences, October 21, 2013 doi:10.1073/pnas.1302653110 No Known Hominin Species Matches the Expected Dental Morphology of the Last Common Ancestor of Neanderthals and Modern Humans Gómez-Roblesa, Aida, José María Bermúdez de Castroc, Juan-Luis Arsuaga, Eudald Carbonelle, and P. David…
Neandertal Admixture in Africans: A Back-Migration to Sub-Saharan Africa Confirmed
Genome Biology and Evolution 2013 Oct 25. Apparent Variation in Neanderthal Admixture among African Populations is Consistent with Gene Flow from non-African Populations. Shuoguo Wang, Joseph Lachance, Sarah Tishkoff, Jody Hey, and Jinchuan Xing Abstract Recent studies have found evidence of…
Reader Questions 1: In Search of Archaic Hominin Survivals in Eurasia. Tutkaul Culture
This is a new category of posts on this weblog. Every now and then a reader sends me a question and sometimes I get interested and try to answer. There seems to be a steady interest on the part of…
An Out-of-America Signal as Seen Through Human Regulatory Genes
PLoS Genet 9(4): e1003404. doi:10.1371/journal.pgen.1003404 Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence Omer Gokcumen, Qihui Zhu, Lubbertus C. F. Mulder, Rebecca C. Iskow, Christian Austermann, Christopher D. Scharer, Towfique Raj, Jeremy M. Boss, Shamil…
Rare Haplotypes in Koreans: Evidence for a Back Migration into Africa?
CAMDA 2012 Conference, July 13, 2012 Rare Haplotypes in the Korean Population Sepp Hochreiter, Gunter Klambauer, Gundula Povysil, and Djork‐Arné Clevert Link (Full Text PDF) These days you never know where research related to modern human origins will be reported…
How Europeans Got to Be ~10% American Indian
Genetics doi: 10.1534/genetics.112.145037 Ancient Admixture in Human History Nick Patterson, Priya Moorjani, Yontao Luo, Swapan Mallick, Nadin Rohland, Yiping Zhan, Teri Genschoreck, Teresa Webster, and David Reich Population mixture is an important process in biology. We present a suite of methods…
A High Coverage of the Denisovan Hominin
Science 30 August 2012 DOI: 10.1126/science.1224344 A High-Coverage Genome Sequence from an Archaic Denisovan Individual Matthias Meyer, Martin Kircher, Marie-Theres Gansauge, Heng Li, Fernando Racimo, Swapan Mallick, Joshua G. Schraiber, Flora Jay, Kay Prüfer, Cesare de Filippo, Peter H. Sudmant,…
Neandertal Admixture in microRNA Genes
Molecular Biology and Evolution (27 January 2012), doi:10.1093/molbev. An Ancestral miR-1304 Allele Present in Neanderthals Regulates Genes Involved in Enamel Formation and Could Explain Dental Differences with Modern Humans Lopez-Valenzuela, Maria, Oscar Ramirez, Antonio Rosas, Samuel Garcıa-Vargas, Marco de la…
Howler Monkeys, Neandertals, Pygmies, Khoisans and More: Society for Molecular Biology and Evolution 2012
As I write, Society for Molecular Biology and Evolution (SMBE) is conducting its annual meetings in Dublin, Ireland. Dienekes has many useful pullouts from the available abstracts. I will make short comments on a few of them, plus bring in…
Neanderthals and Amerindians: Intragroup Genetic Diversity and Population Size
John Hawks writes: “Neandertals have strikingly limited genetic variation. They once lived across a range from Spain to Siberia. Yet when we compare sequences across their whole genomes, we find them to be much less different across this geographic range…
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